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Bioinformatics

 
  Antimicrobial targets

Bacterial Pathogenesis

Bioinformatics

Host pathogen interactions

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Structural & functional biology

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Bioinformatics is the application of computer science, applied mathematics and statistics to solve molecular biological problems.
 
The ARC Centre of Excellence in Structural and Functional Microbial Genomics uses bioinformatic analysis of relevant genome sequences to identify:
 
Potential virulence genes;
Unique genes that may be essential for growth and survival and;
Genes encoding surface exposed or secreted antigens of the bacterial pathogens of interest.
 
The Centre uses WASABI to compare and mine novel genomic data.
 
The Centre is developing a target tracking Laboratory Information Management System (LIMS) to drive automated aspects of the High-throughput Microbial Pipeline.
 
The Centre plans to improve software for proteomics and microarray analysis and develop databases for the integration and analysis of these complex data sets.
 
For further information about the Centre’s methods of bioinformatic/genomic analysis please contact Centre Chief Investigators Professor Ross Coppel or Professor James Whisstock.
 
Australian Research Council
Monash University
Victorian Government
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